Doctor's Best

Doctor's Best, Best Benfotiamine, 360 Veggie Caps

Name: Doctor's Best, Best Benfotiamine, 360 Veggie Caps
Brand: Doctor's Best
Price: 8400.00 INR
Availability: InStock

Rs. 8,400.00

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Size:360 Count (Pack of 1)

Support against oxidative stress. Benfotiamine displays direct antioxidant action in vitro, and preliminary research with human subjects suggests that this activity can be advantageous in helping to safeguard the integrity of human DNA by increasing the antioxidant capacity of plasma. In the laboratory, when human, rat, and porcine kidney cells were exposed to toxins that assault the integrity of DNA, benfotiamine was able to reduce oxidative stress under these circumstances. Benfotiamine, like vitamins C and E, can deter the activation of NF-kB (a DNA-binding factor known to be activated by oxidative stress-generated reactive oxygen species) for more balanced immune responses. Furthermore, recent in vitro results suggest that the beneficial antioxidant properties of benfotiamine could work against some forms of lipid peroxidation. An animal model suggests that during oxidative stress generated by excess glucose, benfotiamine has the capacity to reduce levels of superoxide and hydroxyl radicals in the heart. Similarly, an animal model of induced oxidative stress in the cerebral cortex (the outer most layer of the brain) suggests a beneficial antioxidant effect of benfotiamine. Supports blood levels of thiamin pyrophosphate (TTP), the biologically active co–enzyme form of thiamin* Helps maintain healthy glucose metabolism. Benfotiamine increases blood and tissue levels of thiamin pyrophosphate (TPP), the biologically active co-enzyme form of thiamin. TPP acts as a co-enzyme for three critical enzymes involved in glucose metabolism: 1) transketolase, 2) pyruvate dehydrogenase, and 3) a-ketoglutarate decarboxylase. The latter two enzymes are involved in utilizing glucose for fuel. Thus, TTP is vital to the cell’s energy supply. Stimulates transketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways. Supports healthy aging. Disrupts formation of Advanced Glycation End-Products (AGEs). Helps maintain healthy circulation

From the manufacturer

Doctor’s Best Benfotiamine blood glucose glucose metabolites oxidative stress

*These statements have not been evaluated by the Food and Drug Administration. This product in not intended to diagnose, treat, cure or prevent any disease.

Doctor’s Best Benfotiamine is a fat-soluble form and highly bioavailable derivative of thiamin (Vitamin B1).* Benfotiamine is activated in the bloodstream, and is available in the body four times longer than water-soluble thiamin.* Benfotiamine activates transketolase, a cellular enzyme essential for glucose metabolism pathway.*

It helps support the circulatory and nervous systems with radical-scavenging action against oxidative stress, providing a positive influence on Advanced Glycation End products (AGEs).*


What are the benefits from Benfotiamine? Helps maintain healthy cells in the presence of blood glucose* Provides support against oxidative stress, and supports healthy aging.*	Why take Benfotiamine? Benfotiamine is an ingredient derived from thiamine (a B vitamin also known as vitamin B1).* Benfotiamine can improve levels of thiamine and, protect against health conditions related with low thiamine levels.*	How does it work? Benfotiamine is fat-soluble and more bioavailable and physiologically active than thiamin.* Stimulates transketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways.*

What is Doctor’s Best Benfotiamine?

Benfotiamine (S-benzoylthiamine-O-monophosphate) is a synthetic derivative of thiamin (Vitamin B1) belonging to the family of compounds known as allithiamines. Benfotiamine is fat-soluble and more bioavailable and physiologically active than thiamin.* Benfotiamine helps maintain healthy cells in the presence of blood glucose, provides support against oxidative stress, and supports healthy aging.*

How does it work?

Benfotiamine raises the blood level of thiamin pyrophosphate (TPP), the biologically active coenzyme of thiamin, and stimulates transketolase, a cellular enzyme essential for maintenance of normal glucose metabolic pathways. Benfotiamine can greatly improve thiamin status, especially in comparison with regular forms of thiamin. In a randomized, double-blind crossover trial comparing bioavailability of benfotiamine to that of thiamin mononitrate (the most common supplemental form of vitamin B1) in 12 individuals, benfotiamine caused an average 5-fold greater increase in blood thiamin levels than thiamin mononitrate, with a concomitant greater thiamin concentration in red blood cells. Benfotiamine is converted to S-benzoylthiamin (through removal of the O-monophosphate by the digestive tract), which readily passes through intestinal cells and is converted into thiamin.

Why take Best Benfotiamine?

Benfotiamine is fat-soluble and more bioavailable and physiologically active than thiamin.* Benfotiamine helps maintain healthy cells in the presence of blood glucose, provides support against oxidative stress, and supports healthy aging.* Benfotiamine helps maintain healthy glucose metabolism by increasing blood and tissue levels of thiamine pyrophosphate (TPP), the biologically active co-enzyme form of thiamine.*TPP acts as a co-enzyme for three critical enzymes involved in glucose metabolism: 1) transketolase, 2) pyruvate dehydrogenase, and 3) a-ketogutarate decarboxylase. The latter two enzymes are involved in utilizing glucose for fuel. Thus, TTP is vital to the cell’s energy supply

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Doctor's Best, Best Benfotiamine, 360 Veggie Caps